Article
Investigation of an LDLR gene polymorphism (19p13.2) in susceptibility to migraine without aura.
Journal of the neurological sciences - 15 Sept 2003
Mochi Mirella, Cevoli Sabina, Cortelli Pietro, Pierangeli Giulia, Scapoli Chiara, Soriani Stefano, Montagna Pasquale
Abstract excerpt
We performed a genetic association study with the LDL receptor gene (LDLR) on chromosome 19p13.2 in 360 migraine patients, 220 with migraine without aura (MO) and 140 with migraine with aura (MA), and 200 controls, by analysing two polymorphic markers, a G142A transition in exon 10 and a triallelic (TA)n repeat in exon 18. The allelic distribution of the (TA)n polymorphism was significantly different between...
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