Article
Investigation of the low-density lipoprotein receptor gene and cholesterol as a risk factor for migraine.
Journal of the neurological sciences - 15 Dec 2004
Curtain R, Lea R A, Quinlan S, Bellis C, Tajouri L, Hughes R, Macmillan J, Griffiths L R
Abstract excerpt
The Low-Density Lipoprotein Receptor (LDLR) gene is a cell surface receptor that plays an important role in cholesterol homeostasis. We investigated the (TA)n polymorphism in exon 18 of the LDLR gene on chromosome 19p13.2 performing an association analysis in 244 typical migraine-affected patients, 151 suffering from migraine with aura (MA), 96 with migraine without aura (MO) and 244 unaffected controls. The...
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