Article
Genetic association study of endothelin-1 and its receptors EDNRA and EDNRB in migraine with aura.
Cephalalgia : an international journal of headache - 1 Nov 2009
Tikka-Kleemola P, Kaunisto M A, Hämäläinen E, Todt U, Göbel H, Kaprio J, Kubisch C, Färkkilä M, Palotie A, Wessman M, Kallela M
Abstract excerpt
The effect of endothelin-1 and its receptors EDNRA and EDNRB in migraine with aura (MA) susceptibility is not established yet. We studied the association between the MA end-diagnosis and three migraine trait components and 32 single nucleotide polymorphisms (SNPs) capturing the variation of endothelin genes in 850 Finnish migraine patients and 890 non-migrainous individuals. The SNPs showing evidence of...
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