Article

Estrogen Promotes Early Osteoblast Differentiation and Inhibits Adipocyte Differentiation in Mouse Bone Marrow Stromal Cell Lines that Express Estrogen Receptor (ER) or

2002-06-01

Abstract excerpt

Although cells of the osteoblast lineage express functional ERs, direct effects of estrogen on bone formation remain obscure. In the present study, we have investigated estrogen effects on osteoblastic and adipocytic differentiation from a mouse bone marrow stromal cell line, ST-2, which had been manipulated to overexpress either human ERα (ST2ERα) or ERβ (ST2ERβ). Treatment with bone morphogenetic protein-2 incre...

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Literature Corpus work: ddfa0a32-0e99-5e2a-b7b8-e77d86c9ebb3
DOI: 10.1210/en.143.6.2349

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