Article
Cytotoxic T lymphocyte antigen-4 gene polymorphisms do not confer susceptibility to autoimmune hepatitis types 1 and 2 in Brazil.
The American journal of gastroenterology - 1 Jul 2003
Bittencourt Paulo L, Palácios Selma A, Cançado Eduardo L R, Porta Gilda, Carrilho Flair J, Laudanna Antonio A, Kalil Jorge, Goldberg Anna C
Abstract excerpt
OBJECTIVE: Susceptibility to autoimmune hepatitis (AIH) has been linked to different HLA-DR antigens in distinct populations. Recently, an A-G polymorphism in exon 1 of the cytotoxic T lymphocyte antigen-4 (CTLA-4) gene was associated with predisposition to AIH type 1 (AIH-1) in white individuals in North America. This polymorphism has been associated with several other autoimmune diseases, presumably because of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
