Article
Regulation of maternal transcript destabilization during egg activation in Drosophila.
Genetics - 1 Jul 2003
Tadros Wael, Houston Simon A, Bashirullah Arash, Cooperstock Ramona L, Semotok Jennifer L, Reed Bruce H, Lipshitz Howard D
Abstract excerpt
In animals, the transfer of developmental control from maternal RNAs and proteins to zygotically derived products occurs at the midblastula transition. This is accompanied by the destabilization of a subset of maternal transcripts. In Drosophila, maternal transcript destabilization occurs in the absence of fertilization and requires specific cis-acting instability elements. We show here that egg activation is...
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