Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PAN GU: a protein kinase that inhibits S phase and promotes mitosis in early Drosophila development.

Development (Cambridge, England) - 1 Nov 2000

Fenger D D, Carminati J L, Burney-Sigman D L, Kashevsky H, Dines J L, Elfring L K, Orr-Weaver T L

Abstract excerpt

Following completion of meiosis, DNA replication must be repressed until fertilization. In Drosophila, this replication block requires the products of the pan gu (png), plutonium (plu) and giant nuclei (gnu) genes. These genes also ensure that S phase oscillates with mitosis in the early division...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animals, Genetically Modified
Share to Cyclins
Share to Drosophila

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila Proteins

Share to Genes, Insect

Share to Mitosis

Share to Restriction Mapping

Share to S Phase

Source

Identifiers

PMID: 11044392
DOI: 10.1242/dev.127.22.4763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11044392-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PAN GU: a protein kinase that inhibits S phase and promotes mitosis in early Drosophila development.PMID 11044392Read ↗

The Drosophila cell cycle kinase PAN GU forms an active complex with PLUTONIUM and GNU to regulate embryonic divisions.Semantic proximity Read ↗

giant nuclei is essential in the cell cycle transition from meiosis to mitosis.Semantic proximity Read ↗

A genetic screen for suppressors and enhancers of the Drosophila PAN GU cell cycle kinase identifies cyclin B as a target.Semantic proximity Read ↗

Drosophila PLUTONIUM protein is a specialized cell cycle regulator required at the onset of embryogenesis.Semantic proximity Read ↗

The Drosophila plutonium and pan gu genes regulate entry into S phase at fertilization.Semantic proximity Read ↗

PP2A-twins is antagonized by greatwall and collaborates with polo for cell cycle progression and centrosome attachment to nuclei in drosophila embryos.Semantic proximity Read ↗

Regulation of maternal transcript destabilization during egg activation in Drosophila.Semantic proximity Read ↗

Cloning and characterization of peter pan, a novel Drosophila gene required for larval growth.Semantic proximity Read ↗

Endomitosis controls tissue-specific gene expression during developmentSemantic proximity Read ↗

SMAUG is a major regulator of maternal mRNA destabilization in Drosophila and its translation is activated by the PAN GU kinase.Semantic proximity Read ↗

The RNA-binding protein Tsunagi interacts with Mago Nashi to establish polarity and localize oskar mRNA during Drosophila oogenesis.Semantic proximity Read ↗

Mutations in Drosophila Greatwall/Scant reveal its roles in mitosis and meiosis and interdependence with Polo kinase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.