Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Drosophila plutonium and pan gu genes regulate entry into S phase at fertilization.

Cell - 20 Sept 1991

Shamanski F L, Orr-Weaver T L

Abstract excerpt

Mutations in the Drosophila maternal genes plutonium (plu) and pan gu (png) have the striking phenotype that DNA replication initiates in unfertilized eggs. Fertilized eggs from plu or png mutant mothers also have a mutant phenotype; DNA replication is uncoupled from nuclear division, resulting in giant, polyploid nuclei. Analysis of multiple alleles of these genes indicates that their wild-type function is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Cell Cycle
Share to DNA Replication

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Genetic Complementation Test

Share to Mitosis

Share to Mutation

Source

Identifiers

PMID: 1913810
DOI: 10.1016/0092-8674(91)90050-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

The Drosophila plutonium and pan gu genes regulate entry into S phase at fertilization.PMID 1913810Read ↗

Drosophila PLUTONIUM protein is a specialized cell cycle regulator required at the onset of embryogenesis.Semantic proximity Read ↗

PAN GU: a protein kinase that inhibits S phase and promotes mitosis in early Drosophila development.Semantic proximity Read ↗

The Drosophila cell cycle kinase PAN GU forms an active complex with PLUTONIUM and GNU to regulate embryonic divisions.Semantic proximity Read ↗

giant nuclei is essential in the cell cycle transition from meiosis to mitosis.Semantic proximity Read ↗

A genetic screen for suppressors and enhancers of the Drosophila PAN GU cell cycle kinase identifies cyclin B as a target.Semantic proximity Read ↗

Regulation of maternal transcript destabilization during egg activation in Drosophila.Semantic proximity Read ↗

Luna, a Drosophila KLF6/KLF7, is maternally required for synchronized nuclear and centrosome cycles in the preblastoderm embryo.Semantic proximity Read ↗

Altered dynein-dependent transport in piRNA pathway mutants.Semantic proximity Read ↗

A maternal requirement for glutamine synthetase I for the mitotic cycles of syncytial Drosophila embryos.Semantic proximity Read ↗

Mutations in new cell cycle genes that fail to complement a multiply mutant third chromosome of Drosophila.Semantic proximity Read ↗

Interactions between mgr, asp, and polo: asp function modulated by polo and needed to maintain the poles of monopolar and bipolar spindles.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.