The Drosophila plutonium and pan gu genes regulate entry into S phase at fertilization.

doi:10.1016/0092-8674(91)90050-9

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Article

The Drosophila plutonium and pan gu genes regulate entry into S phase at fertilization.

Cell - 20 Sept 1991

Shamanski F L, Orr-Weaver T L

Abstract excerpt

Mutations in the Drosophila maternal genes plutonium (plu) and pan gu (png) have the striking phenotype that DNA replication initiates in unfertilized eggs. Fertilized eggs from plu or png mutant mothers also have a mutant phenotype; DNA replication is uncoupled from nuclear division, resulting i...

Topics

Alleles
Animals
Cell Cycle
Cleavage Stage, Ovum
DNA Replication
Drosophila melanogaster
Fertilization
Genes
Genes, Regulator
Genetic Complementation Test
Mitosis
Mutation

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