Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

giant nuclei is essential in the cell cycle transition from meiosis to mitosis.

Development (Cambridge, England) - 1 Jul 2003

Renault Andrew D, Zhang Xiao-Hua, Alphey Luke S, Frenz Lisa M, Glover David M, Saunders Robert D C, Axton J Myles

Abstract excerpt

At the transition from meiosis to cleavage mitoses, Drosophila requires the cell cycle regulators encoded by the genes, giant nuclei (gnu), plutonium (plu) and pan gu (png). Embryos lacking Gnu protein undergo DNA replication and centrosome proliferation without chromosome condensation or mitotic segregation. We have identified the gnu gene encoding a novel phosphoprotein dephosphorylated by Protein phosphatase 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Infertility
Share to Meiosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mitosis

Share to Oocytes

Share to Protein Processing, Post-Translational

Share to Transgenes

Source

Identifiers

PMID: 12756181
DOI: 10.1242/dev.00501

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

giant nuclei is essential in the cell cycle transition from meiosis to mitosis.PMID 12756181Read ↗

PAN GU: a protein kinase that inhibits S phase and promotes mitosis in early Drosophila development.Semantic proximity Read ↗

The Drosophila cell cycle kinase PAN GU forms an active complex with PLUTONIUM and GNU to regulate embryonic divisions.Semantic proximity Read ↗

Drosophila PLUTONIUM protein is a specialized cell cycle regulator required at the onset of embryogenesis.Semantic proximity Read ↗

The Drosophila plutonium and pan gu genes regulate entry into S phase at fertilization.Semantic proximity Read ↗

A genetic screen for suppressors and enhancers of the Drosophila PAN GU cell cycle kinase identifies cyclin B as a target.Semantic proximity Read ↗

Regulation of maternal transcript destabilization during egg activation in Drosophila.Semantic proximity Read ↗

Endomitosis controls tissue-specific gene expression during developmentSemantic proximity Read ↗

The GNU subunit of PNG kinase, the developmental regulator of mRNA translation, binds BIC-C to localize to RNP granules.Semantic proximity Read ↗

The diverse functions of germline P‐granules in Caenorhabditis elegansSemantic proximity Read ↗

Connecting the Dots: Linking Caenorhabditis elegans Small RNA Pathways and Germ Granules.Semantic proximity Read ↗

The Drosophila prage Gene, Required for Maternal Transcript Destabilization in Embryos, Encodes a Predicted RNA Exonuclease.Semantic proximity Read ↗

Maternal Proteins That Are Phosphoregulated upon Egg Activation Include Crucial Factors for Oogenesis, Egg Activation and Embryogenesis in Drosophila melanogasterSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.