Article
[Relationship between mutation on precore region of integrated HBV DNA and p53 gene mutation in hepatocellular carcinoma].
Ai zheng = Aizheng = Chinese journal of cancer - 1 Jul 2003
Wang Xiu-Hai, Wang Pei-Lin
Abstract excerpt
BACKGROUND & OBJECTIVE: The chronic infection of hepatitis B virus (HBV) is a recognized risk factor for the development of hepatocellular carcinoma (HCC); however, the precise mechanism of carcinogenesis is unknown. In order to better understand the molecular mechanism of hepatocarcinogenesis, this study was designed to investigate the relationship between the gene mutation on precore region of integrated HBV...
Topics
- Adult
- Aged
- Carcinoma, Hepatocellular
- DNA, Viral
- Female
- Genes, p53
- Hepatitis B virus
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Virus Integration
