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Article

[Association of pre-core defective HBV mutant with anti-HBe positive chronic hepatitis].

Nihon rinsho. Japanese journal of clinical medicine - 1 Feb 1993

Karasawa T, Aizawa Y, Zeniya M, Toda G

Abstract excerpt

Precore defective HBV mutant has been suggested to be responsible for the pathogenesis of fulminant hepatitis. This variant is unable to produce HBeAg because of the presence of a novel translational stop codon at the end of the precore region of the genome. We examined the precore region of the HBV nucleotide sequence in 12 Japanese anti-HBe positive chronic hepatitis patients in order to ascertain whether the...

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PMID: 8464147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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[Association of pre-core defective HBV mutant with anti-HBe positive chronic hepatitis].PMID 8464147Read ↗

Association between frequency of amino acid changes in core region of hepatitis B virus (HBV) and the presence of precore mutation in Japanese HBV carriers.Semantic proximity Read ↗

[Clinical significance of hepatitis B virus precore/core mutants in HBe-antigen-positive and anti-HBe-positive chronic hepatitis B].Semantic proximity Read ↗

[Nucleotide sequence analysis of the hepatitis B virus X-precore region in chronic hepatitis B].Semantic proximity Read ↗

Association of hepatitis B viral precore mutations with fulminant hepatitis B in Japan.Semantic proximity Read ↗

Universal emergence of precore mutant hepatitis B virus along with seroconversion to anti-HBe irrespective of subsequent activity of chronic hepatitis B.Semantic proximity Read ↗

Response to interferon-alpha in chronic hepatitis B with and without precore mutant strain detected by mutation site-specific assay.Semantic proximity Read ↗

Hepatitis may precede the occurrence of precore region mutation in hepatitis B virus genome during infection in young carriers.Semantic proximity Read ↗

Point mutation in precore region of hepatitis B virus: sequential changes from 'wild' to 'mutant'.Semantic proximity Read ↗

[Low frequency of precore stop mutation in patients with dual infection of hepatitis B and C viruses].Semantic proximity Read ↗

Low frequency of precore hepatitis B virus mutants in anti-hepatitis B e-positive reactivation after loss of hepatitis B e antigen in patients with chronic hepatitis B.Semantic proximity Read ↗

[Therapeutic effect of levamisole plus HBV vaccine and dipyridamole on patients chronically infected by HBV with precore mutation].Semantic proximity Read ↗

Detection of precore/core-mutant hepatitis B virus genome in patients with acute or fulminant hepatitis without serological markers for recent HBV infection.Semantic proximity Read ↗

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