Article
[Influence of mutation in HBV precore region on the expression of HLA-I in HepG2 cells].
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Oct 2002
Chen Weihong, Lin Yulong, Luo Kangxian, Hou Jinlin
Abstract excerpt
OBJECTIVE: To study the influence of host cellular HLA-I molecules expression by HBV precore region mutants. METHODS: The plasmids of the wild type of HBV precore region and the mutants of A83 and A83/A86 were constructed, and then transected into HepG2 cells. The biological activity of HBV precore gene in the host cells was identified. The expression of HLA-I molecules was detected by flow cytometric analysis....
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