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Article

Single-nucleotide polymorphisms in uncoding regions of ALS2 gene of Japanese patients with autosomal-recessive amyotrophic lateral sclerosis.

Neurological research - 1 Jul 2003

Nagano Isao, Murakami Tetsuro, Shiote Mito, Manabe Yasuhiro, Hadano Shinji, Yanagisawa Yoshiko, Ikeda Joh-E, Abe Koji

Abstract excerpt

ALS2 is an autosomal recessive form of amyotrophic lateral sclerosis (AR-ALS) with juvenile onset, and has been mostly found in North African and Middle Eastern countries. Deletion mutations in the coding exons of a new gene ALS2, encoding a protein with guanine-nucleotide exchange factor (GEF) d...

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Source

Identifiers

PMID: 12866199
DOI: 10.1179/016164103101201733

Genes

ALS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12866199-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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