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Article

Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.

Neurobiology of aging - 1 Apr 2012

Iida Aritoshi, Kamei Tetsumasa, Sano Motoki, Oshima Shuichi, Tokuda Torao, Nakamura Yusuke, Ikegawa Shiro

Abstract excerpt

Mutations in TARDBP encoding TDP (TAR DNA binding protein)-43 have been reported in familial and sporadic amyotrophic lateral sclerosis (ALS), but mostly in Caucasians. In other ethnic groups, four types of mutations are found in familial ALS. In sporadic ALS, the TARDBP mutations frequency is lo...

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Source

Identifiers

PMID: 20675015
DOI: 10.1016/j.neurobiolaging.2010.06.017

Genes

TARDBP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20675015-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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