Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Intermediate-length polyglutamine in ATXN2 is a possible risk factor among Eastern Chinese patients with amyotrophic lateral sclerosis.

Neurobiology of aging - 1 Mar 2015

Lu Hai-Peng, Gan Shi-Rui, Chen Sheng, Li Hong-Fu, Liu Zhi-Jun, Ni Wang, Wang Ning, Wu Zhi-Ying

Abstract excerpt

An effective treatment for amyotrophic lateral sclerosis (ALS) has not yet been found because the pathogenesis of this fatal disease is not well understood. A number of previous studies demonstrated that intermediate-length polyglutamine repeats within the ataxin-2 gene (ATXN2) might be a risk factor among patients with ALS in Western countries. Here, we aim to determine whether this sequence is a risk factor in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Amyotrophic Lateral Sclerosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Genetic Association Studies

Share to Peptides

Share to Risk Factors

Share to Trinucleotide Repeat Expansion

Share to Young Adult

Source

Identifiers

PMID: 25457026
DOI: 10.1016/j.neurobiolaging.2014.10.015

Genes

ATXN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Intermediate-length polyglutamine in ATXN2 is a possible risk factor among Eastern Chinese patients with amyotrophic lateral sclerosis.PMID 25457026Read ↗

Intermediate-length CAG repeat in ATXN2 is associated with increased risk for amyotrophic lateral sclerosis in Brazilian patients.Semantic proximity Read ↗

Intermediate CAG repeat expansion in the ATXN2 gene is a unique genetic risk factor for ALS--a systematic review and meta-analysis of observational studies.Semantic proximity Read ↗

Ataxin-2 intermediate-length polyglutamine: a possible risk factor for Chinese patients with amyotrophic lateral sclerosisSemantic proximity Read ↗

Amyotrophic Lateral Sclerosis Risk for Spinocerebellar Ataxia Type 2 ATXN2 CAG Repeat AllelesSemantic proximity Read ↗

ATXN2 CAG repeat expansions increase the risk for Chinese patients with amyotrophic lateral sclerosisSemantic proximity Read ↗

Intermediate Repeat Expansion in ATXN2 Gene as a Risk Factor in ALS and FTD Spanish PopulationSemantic proximity Read ↗

Intermediate Repeat Expansion in the ATXN2 Gene as a Risk Factor in the ALS and FTD Spanish PopulationSemantic proximity Read ↗

ATXN2 trinucleotide repeat length correlates with risk of ALS.Semantic proximity Read ↗

ATXN2 intermediate expansions in amyotrophic lateral sclerosis.Semantic proximity Read ↗

ATAXIN2 CAG-repeat length in Italian patients with amyotrophic lateral sclerosis: risk factor or variant phenotype? Implication for genetic testing and counseling.Semantic proximity Read ↗

Association of long ATXN2 CAG repeat sizes with increased risk of amyotrophic lateral sclerosis.Semantic proximity Read ↗

ATXN2 and its neighbouring gene SH2B3 are associated with increased ALS risk in the Turkish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.