Article
Fitness of antibiotic resistant Staphylococcus epidermidis assessed by competition on the skin of human volunteers.
The Journal of antimicrobial chemotherapy - 1 Aug 2003
Gustafsson Ingegerd, Cars Otto, Andersson Dan I
Abstract excerpt
BACKGROUND: Antibiotic resistance typically confers a biological fitness cost on bacteria that can be manifested as a decreased growth rate in culture media and experimental animals. However, there are limited experimental data on the relative fitness of resistant and susceptible bacteria during growth in their natural environment. OBJECTIVE: We have developed a human competition model to investigate the relative...
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