Article
Human estrogen receptor beta 548 is not a common variant in three distinct populations.
Endocrinology - 1 Aug 2003
Xu Li, Pan-Hammarström Qiang, Försti Asta, Hemminki Kari, Hammarström Lennart, Labuda Damian, Gustafsson Jan-Ake, Dahlman-Wright Karin
Abstract excerpt
Several isoforms of estrogen receptor (ER) beta (also known as NR3A2) have been reported, including variants with different N-terminal ends. In rodents, two in-frame initiation codons (ATGs) are used to produce proteins of 530 and 549 amino acids, respectively. In humans, the upstream ATG is out of frame in all clones reported, until recently, when human clones with an extra A-T base pair placing the upstream ATG...
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