Article
ERbeta1 and the ERbeta2 splice variant (ERbetacx/beta2) are expressed in distinct cell populations in the adult human testis.
The Journal of clinical endocrinology and metabolism - 1 Jun 2002
Saunders Philippa T K, Millar Michael R, Macpherson Sheila, Irvine D Stewart, Groome Nigel P, Evans Lee R, Sharpe Richard M, Scobie Graeme A
Abstract excerpt
Estrogens can regulate germ cell function. Estrogen action is mediated via high affinity ERs; two subtypes (ERalpha and ERbeta) have been identified. We have shown previously that ERbeta is expressed in nuclei of multiple human testicular cells. A variant isoform of human (h) ERbeta (hERbetacx/2), formed by alternative splicing, has been identified in testicular cDNA libraries by two laboratories. The present...
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