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Article

Gene expression pattern of laser microdissected colonic crypts of adenomas with low grade dysplasia

15 Jul 2003

Abstract excerpt

BACKGROUND AND AIMS: Colorectal epithelial cells are prone to malignant transformation. Therefore, identification of differences in gene expression in the process from normal colonic crypts to adenomas with low grade dysplasia is essential for further insights into early tumorigenesis. To achieve this goal, a novel gene expression analysis strategy, screening for expressed transcripts in small histologically...

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PMID: 12865273
DOI: 10.1136/gut.52.8.1148

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