Article
Recurrence risk modelling of the genetic susceptibility to ankylosing spondylitis.
Annals of the rheumatic diseases - 1 Nov 2000
Brown M A, Laval S H, Brophy S, Calin A
Abstract excerpt
OBJECTIVES: It has long been suspected that susceptibility to ankylosing spondylitis (AS) is influenced by genes lying distant to the major histocompatibility complex. This study compares genetic models of AS to assess the most likely mode of inheritance, using recurrence risk ratios in relatives of affected subjects. METHODS: Recurrence risk ratios in different degrees of relatives were determined using...
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