Article
Chloroquine and artemisinin: six decades of research--what next?
IDrugs : the investigational drugs journal - 1 Jul 2003
Delhaes Laurence, Benoit-Vical Françoise, Camus Daniel, Capron Monique, Meunier Bernard
Abstract excerpt
Over the next decade drugs will remain the focus of continuous efforts to control malaria, with a contribution from pharmacogenomic development. Quinine, extracted from Cinchona bark, has been the source for aminoquinoline drugs such as chloroquine; more recently, artemisinin extracted from Artemisia allowed the design of artemisinin mimics containing a trioxane structure. Here, we examine parallels between...
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