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Article

Regulation of quiescence in lymphocytes.

Trends in immunology - 1 Jul 2003

Yusuf Isharat, Fruman David A

Abstract excerpt

Cellular quiescence is a state characterized by decreased cell size and metabolic activity. In quiescent nai;ve lymphocytes, antigen recognition with appropriate co-stimulation triggers exit from G0 phase of the cell cycle, increased size and metabolism and progression through the cell cycle. Recent studies have shown that quiescence in lymphocytes is an actively maintained state rather than a default pathway in...

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PMID: 12860529
DOI: 10.1016/s1471-4906(03)00141-8

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