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Modelling mammalian cellular quiescence

25 Apr 2014

Abstract excerpt

Cellular quiescence is a reversible non-proliferating state. The reactivation of 'sleep-like' quiescent cells (e.g. fibroblasts, lymphocytes and stem cells) into proliferation is crucial for tissue repair and regeneration and a key to the growth, development and health of higher multicellular organisms, such as mammals. Quiescence has been a primarily phenotypic description (i.e. non-permanent cell cycle arrest)...

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PMID: 24904737
DOI: 10.1098/rsfs.2013.0074

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