Article
SNAP-25 and gene-targeted mouse mutants.
Annals of the New York Academy of Sciences - 1 Jan 2009
Bark Christina
Abstract excerpt
The evolutionary conserved soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) fusion machinery is the operational unit in the release of neurotransmitters and hormones from excitable cells. The SNARE core complex consists of three proteins named SNAP-25 (synaptosomal-associated protein of 25 kD), syntaxin 1, and VAMP (vesicle-associated membrane protein)/synaptobrevin. Syntaxin 1 is,...
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