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Article

Fanconi anemia type C and p53 cooperate in apoptosis and tumorigenesis.

Blood - 1 Dec 2003

Freie Brian, Li Xiaxin, Ciccone Samantha L M, Nawa Kathy, Cooper Scott, Vogelweid Catherine, Schantz Laurel, Haneline Laura S, Orazi Attilio, Broxmeyer Hal E, Lee Suk-Hee, Clapp D Wade

Abstract excerpt

Fanconi anemia (FA) is a recessive genomic instability syndrome characterized by developmental defects, progressive bone marrow failure, and cancer. FA is genetically heterogeneous, however; the proteins encoded by different FA loci interact functionally with each other and with the BRCA1, BRCA2, and ATM gene products. Although patients with FA are highly predisposed to the development of myeloid leukemia and...

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Source

Identifiers

PMID: 12855557
DOI: 10.1182/blood-2003-03-0971

Genes

ATM
BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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