Article
Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy.
Current cancer drug targets - 1 Feb 2009
Andreassen Paul R, Ren Keqin
Abstract excerpt
DNA interstrand crosslinkers, a chemically diverse group of compounds which also induce alkylation of bases and DNA intrastrand crosslinks, are extensively utilized for cancer therapy. Understanding the cellular response to DNA damage induced by these agents is critical for more effective utiliza...
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