Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy.

Current cancer drug targets - 1 Feb 2009

Andreassen Paul R, Ren Keqin

Abstract excerpt

DNA interstrand crosslinkers, a chemically diverse group of compounds which also induce alkylation of bases and DNA intrastrand crosslinks, are extensively utilized for cancer therapy. Understanding the cellular response to DNA damage induced by these agents is critical for more effective utilization of these compounds and for the identification of novel therapeutic targets. Importantly, the repair of DNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Damage
Share to DNA Repair
Share to Fanconi Anemia Complementation Group Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Silencing

Share to Mutation

Share to Neoplasms

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 19200054
DOI: 10.2174/156800909787314011
PMCID: PMC4934657

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fanconi anemia proteins, DNA interstrand crosslink repair pathways, and cancer therapy.PMID 19200054Read ↗

Comprehensive review on Fanconi anemia: insights into DNA interstrand cross-links, repair pathways, and associated tumorsSemantic proximity Read ↗

DNA crosslinking damage and cancer - a tale of friend and foe.Semantic proximity Read ↗

Exploiting the Fanconi Anemia Pathway for Targeted Anti-Cancer TherapySemantic proximity Read ↗

DNA repair: exploiting the Fanconi anemia pathway as a potential therapeutic target.Semantic proximity Read ↗

Expanded roles of the Fanconi anemia pathway in preserving genomic stability.Semantic proximity Read ↗

Fanconi Anemia Pathway in Colorectal Cancer: A Novel Opportunity for Diagnosis, Prognosis and TherapySemantic proximity Read ↗

Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.Semantic proximity Read ↗

Emerging functions of the Fanconi anemia pathway at a glance.Semantic proximity Read ↗

Recent insights into the molecular basis of Fanconi anemia: genes, modifiers, and drivers.Semantic proximity Read ↗

Fanconi anemia and DNA repair.Semantic proximity Read ↗

The Fanconi anaemia pathway orchestrates incisions at sites of crosslinked DNA.Semantic proximity Read ↗

Fanconi anaemia and cancer: an intricate relationship.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.