Article
Molecular screening and association studies of retinoid-related orphan receptor gamma (RORC): a positional and functional candidate for type 2 diabetes.
Molecular genetics and metabolism - 1 Jul 2003
Wang Hua, Chu Winston, Das Swapan K, Zheng Zhengxian, Hasstedt Sandra J, Elbein Steven C
Abstract excerpt
The retinoid-related orphan receptor gamma (RORC) is a member of the nuclear hormone superfamily which maps to the 1q21-q23 region. Linkage of type 2 diabetes (T2DM) to this region is well replicated. Several factors argue that RORC is a strong candidate for T2DM susceptibility within this region. RORC may form heterodimers with peroxisome-proliferator activated receptor gamma, it is expressed at high levels in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
