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Article

Mutation screening and association of human retinoid X receptor gamma variation with lipid levels in familial type 2 diabetes.

Molecular genetics and metabolism - 1 May 2002

Wang Hua, Chu Winston, Hemphill Christopher, Hasstedt Sandra J, Elbein Steven C

Abstract excerpt

Both type 2 diabetes (T2DM) and familial combined hyperlipidemia have been mapped to human chromosome 1q21-q24. This region includes the retinoid X receptor gamma (RXRgamma), which is a strong candidate for both glucose and lipid metabolism. Retinoid X receptors form heterodimers with a variety of nuclear receptors, including peroxisome-proliferator-activated receptors alpha and gamma (PPARalpha and PPARgamma),...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12175776
DOI: 10.1016/s1096-7192(02)00016-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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