Article
The 5' terminal oligopyrimidine tract of human elongation factor 1A-1 gene functions as a transcriptional initiator and produces a variable number of Us at the transcriptional level.
Gene - 5 Jun 2003
Shibui-Nihei Akiko, Ohmori Yoshihiro, Yoshida Kenichi, Imai Jun-ichi, Oosuga Ikurou, Iidaka Makoto, Suzuki Yutaka, Mizushima-Sugano Junko, Yoshitomo-Nakagawa Kiyomi, Sugano Sumio
Abstract excerpt
The human elongation factor 1A-1 (eEF1A-1) gene is a member of the 5' terminal oligopyrimidine tract (5' TOP) gene family, and the number of thymidines (Ts) at the 5' TOP of cDNAs corresponding to this gene is known to show variation. Here we determined the 5'-end sequences of 125 eEF1A-1 clones and the complete sequences of 19 eEF1A-1 clones from an oligo-capped cDNA library and showed that variation in the...
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