Article
High-throughput single-nucleotide polymorphism analysis of the IL1RN locus in patients with ankylosing spondylitis by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry.
Arthritis and rheumatism - 1 Jul 2003
Maksymowych Walter P, Reeve Jeff P, Reveille John D, Akey Joshua M, Buenviaje Heidi, O'Brien Lori, Peloso Paul M, Thomson Glen T, Jin Li, Russell Anthony S
Abstract excerpt
OBJECTIVE: To examine single-nucleotide polymorphisms (SNPs) in the 3' region of the IL1RN gene in a large Caucasoid case-control series and in ankylosing spondylitis (AS) families from Western Canada by use of high-throughput MassArray matrix-assisted laser desorption ionization-time-of-flight (MALDI-TOF) mass spectrometry SNP typing. METHODS: An association analysis was performed in a case-control cohort of 394...
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