Article
Low levels of mannose-binding lectin confers protection against tuberculosis in Turkish children.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Dec 2008
Cosar H, Ozkinay F, Onay H, Bayram N, Bakiler A R, Anil M, Can D, Ozkinay C
Abstract excerpt
Mannose-binding lectin (MBL) plays an important role in innate immunity mediating phagocytosis and activating the MBL complement pathway. Few studies, conducted in adult populations, have shown that genetically determined low MBL levels may confer partial protection against tuberculosis (TB). In this study we aimed to investigate the relationships between the susceptibility to TB and two low producing MBL2 gene...
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