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Article

Variant G57E of mannose binding lectin associated with protection against tuberculosis caused by Mycobacterium africanum but not by M. tuberculosis.

PloS one - 1 Jan 2011

Thye Thorsten, Niemann Stefan, Walter Kerstin, Homolka Susanne, Intemann Christopher D, Chinbuah Margaret Amanua, Enimil Anthony, Gyapong John, Osei Ivy, Owusu-Dabo Ellis, Rüsch-Gerdes Sabine, Horstmann Rolf D, Ehlers Stefan, Meyer Christian G

Abstract excerpt

Structural variants of the Mannose Binding Lectin (MBL) cause quantitative and qualitative functional deficiencies, which are associated with various patterns of susceptibility to infectious diseases and other disorders. We determined genetic MBL variants in 2010 Ghanaian patients with pulmonary tuberculosis (TB) and 2346 controls and characterized the mycobacterial isolates of the patients. Assuming a recessive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21695215
DOI: 10.1371/journal.pone.0020908
PMCID: PMC3112207

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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