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Article

Adenovirus-mediated overexpression of caveolin-3 inhibits rat cardiomyocyte hypertrophy.

Hypertension (Dallas, Tex. : 1979) - 1 Aug 2003

Koga Akimasa, Oka Naoki, Kikuchi Toshio, Miyazaki Hiroshi, Kato Seiya, Imaizumi Tsutomu

Abstract excerpt

Caveolae are omega-shaped organelles of the cell surface. The protein caveolin-3, a structural component of cardiac caveolae, is associated with cellular signaling. To investigate the effect of adenovirus-mediated overexpression of caveolin-3 on hypertrophic responses in cardiomyocytes, we constructed an adenovirus that encoded human wild-type caveolin-3 (Ad.Cav-3), mutant caveolin-3 (Ad.Cav-3Delta), or bacterial...

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PMID: 12847114
DOI: 10.1161/01.HYP.0000082926.08268.5D

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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