Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of Gene Transcription by Voltage-gated L-type Calcium Channel, Cav1.3

24 Dec 2014

Abstract excerpt

Cav1.3 L-type Ca(2+) channel is known to be highly expressed in neurons and neuroendocrine cells. However, we have previously demonstrated that the Cav1.3 channel is also expressed in atria and pacemaking cells in the heart. The significance of the tissue-specific expression of the channel is underpinned by our previous demonstration of atrial fibrillation in a Cav1.3 null mutant mouse model. Indeed, a recent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac electrophysiology and arrhythmias
Share to Ion channel regulation and function
Share to Neuroscience and Neural Engineering

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25538241
DOI: 10.1074/jbc.m114.586883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of Gene Transcription by Voltage-gated L-type Calcium Channel, Cav1.3PMID 25538241Read ↗

Caveolin-3: a molecular insight into diseases of the heartSemantic proximity Read ↗

Critical roles of a small conductance Ca²⁺-activated K⁺ channel (SK3) in the repolarization process of atrial myocytes.Semantic proximity Read ↗

CaV3.3 Channelopathies.Semantic proximity Read ↗

Electrophysiological abnormalities associated with a <i>CACNA1D</i> variant are rescued by AAV6-Cav1.3-C-terminus gene therapy in patient-iPSC-CMsSemantic proximity Read ↗

Caveolin-3 and Caveolin-1 Interaction Decreases Channel Dysfunction Due to Caveolin-3 Mutations.Semantic proximity Read ↗

The expression of the rare caveolin-3 variant T78M alters cardiac ion channels function and membrane excitability.Semantic proximity Read ↗

Involvement of Dominant-negative Spliced Variants of the Intermediate Conductance Ca2+-activated K+ Channel, KCa3.1, in Immune Function of Lymphoid CellsSemantic proximity Read ↗

Divergent regulation of cardiac KCND3 potassium channel expression by the thyroid hormone receptors alpha1 and beta1.Semantic proximity Read ↗

Differential expression of small-conductance Ca<sup>2+</sup>-activated K<sup>+</sup>channels SK1, SK2, and SK3 in mouse atrial and ventricular myocytesSemantic proximity Read ↗

Caveolin-3 T78M and T78K missense mutations lead to different phenotypes in vivo and in vitro.Semantic proximity Read ↗

Functional interaction of the two-pore domain potassium channel TASK-1 and caveolin-3.Semantic proximity Read ↗

Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.