Article
Expression of TRbeta1 mRNAs with functionally impaired mutations is rare in thyroid papillary carcinoma.
The Journal of clinical endocrinology and metabolism - 1 Jul 2003
Takano Toru, Miyauchi Akira, Yoshida Hiroshi, Nakata Yukiko, Kuma Kanji, Amino Nobuyuki
Abstract excerpt
A previous study reported the expression of functionally impaired thyroid hormone receptor (TR)beta1 mutants in almost all papillary thyroid carcinomas. To confirm this, we analyzed the sequence of the entire coding region of TRbeta1 cDNAs expressed in 16 papillary carcinomas. Among the 48 clones...
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