Article
Development and characterization of a model system to study amphibian immune responses to iridoviruses.
Virology - 5 Jul 2003
Gantress Jennifer, Maniero Gregory D, Cohen Nicholas, Robert Jacques
Abstract excerpt
The recent realization that viruses within the family Iridoviridae may contribute to the worldwide decline in amphibians makes it urgent to understand amphibian antiviral immune defenses. We present evidence that establishes the frog Xenopus laevis as an important model with which to study anti-iridovirus immunity. Adults resist high doses of FV3 infection, showing only transitory signs of pathology. By contrast,...
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