Article
Interhelical hydrogen bonds in transmembrane region are important for function and stability of Ca2+-transporting ATPase.
Cell biochemistry and biophysics - 1 Jan 2003
Adamian Larisa, Liang Jie
Abstract excerpt
Ca2+-transporting adenosine triphosphatase (ATPase) of sarcoplasmic reticulum couples ATP hydrolysis with ion transport. Phosphorylation of the cytosolic region of the calcium-bound conformation (E1) of the protein leads to drastic conformational rearrangements of the transmembrane helices and th...
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