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Changes in histone acetylation during mouse oocyte meiosis

30 Jun 2003

Abstract excerpt

We examined global changes in the acetylation of histones in mouse oocytes during meiosis. Immunocytochemistry with specific antibodies against various acetylated lysine residues on histones H3 and H4 showed that acetylation of all the lysines decreased to undetectable or negligible levels in the oocytes during meiosis, whereas most of these lysines were acetylated during mitosis in preimplantation embryos and...

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Share to Epigenetics and DNA Methylation
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PMID: 12835313
DOI: 10.1083/jcb.200303047

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