Article
Identification of an autoantigen on the surface of apoptotic human T cells as a new protein interacting with inflammatory group IIA phospholipase A2.
Blood - 15 Oct 2003
Boilard Eric, Bourgoin Sylvain G, Bernatchez Chantale, Surette Marc E
Abstract excerpt
One of the most studied secreted phospholipases A2 (sPLA2), the group IIA sPLA2, is found at high levels in inflammatory fluids of patients with autoimmune diseases. A characteristic of group IIA sPLA2 is its preference for negatively charged phospholipids, which become exposed on the extracellul...
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