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Article

Tryptophan properties in fluorescence and functional stability of plasminogen activator inhibitor 1.

Biophysical journal - 1 Jul 2003

Verheyden Stefan, Sillen Alain, Gils Ann, Declerck Paul J, Engelborghs Yves

Abstract excerpt

Plasminogen activator inhibitor 1 harbors four tryptophan residues at positions 86, 139, 175, and 262. To investigate the contribution of each tryptophan residue to the total fluorescence and to reveal the mutual interactions of the tryptophan residues and interactions with the other amino acids, 15 mutants in which tryptophan residues have been replaced by phenylalanines were constructed, purified, and...

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Identifiers

PMID: 12829505
DOI: 10.1016/S0006-3495(03)74495-6
PMCID: PMC1303106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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