Article
HLA-B27 subtypes determination in patients with ankylosing spondylitis from Zulia, Venezuela.
Human immunology - 1 Jul 2003
Cipriani Ana, Rivera Sergio, Hassanhi Manzur, Márquez Georgina, Hernández Rosaura, Villalobos Cecilia, Montiel Milagros
Abstract excerpt
To perform an investigation regarding the distribution of the human leukocyte antigen (HLA)-B27 subtypes in the Zulian population with ankylosing spondylitis (AS), 48 unrelated Mestizos, HLA-B27 positive by serology, were studied using the polymerase chain reaction-specific sequence oligonucleotides probe (PCR-SSOP) and specific sequence primers (SSP) to analyze the polymorphism in exons 2 and 3 of the HLA-B27...
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