Distribution of HLA-B27 subtypes in ankylosing spondylitis in an Israeli population.

doi:10.1016/j.arcmed.2006.12.001

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Article

Distribution of HLA-B27 subtypes in ankylosing spondylitis in an Israeli population.

Archives of medical research - 1 May 2007

Alaez Carmen, Gazit Ephraim, Ibarrola Blanca, Yaron Michael, Livneh Avi, Avishai Ophelia, Gorodezky Clara

Abstract excerpt

BACKGROUND: The aim of this study was to investigate the contribution of the B27 subtypes to ankylosing spondylitis (AS) expression in a group of Jewish patients from Israel and to compare their distribution with that found in Mexican Mestizo patients. Several HLA-B27 alleles have been clearly associated with AS. Among them, B( *)2705 and B( *)2702 are involved in susceptibility in different populations...

Topics

Adult
Female
Gene Frequency
Genetic Predisposition to Disease
HLA-B27 Antigen
Humans
Israel
Jews
Male
Population
Spondylitis, Ankylosing

Source

Open in PubMed

Identifiers

PMID: 17416294
DOI: 10.1016/j.arcmed.2006.12.001

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