Article
MCP-1 promoter polymorphism in Spanish patients with rheumatoid arthritis.
Human immunology - 1 Jul 2003
González-Escribano Maria Francisca, Torres Belén, Aguilar Francisco, Rodríguez Rosa, García Alicia, Valenzuela Angel, Núñez-Roldán Antonio
Abstract excerpt
To investigate the possible role of the polymorphism located in the regulatory region of monocyte chemoattractant protein-1 (MCP-1) gene in the susceptibility to rheumatoid arthritis (RA), a total of 141 Spanish RA patients and 194 controls, previously typed for human leukocyte antigen DRB1* (HLA-DRB1*), were genotyped for -2518 (A/G) MCP-1 gene polymorphism using polymerase chain reaction-restriction fragment...
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