Article
The -2518 A/G polymorphism in the monocyte chemoattractant protein 1 gene is associated with the risk of developing systemic lupus erythematosus in Argentinean patients: a multicenter study.
European cytokine network - 1 Mar 2012
Aranda Federico, Wingeyer Silvia Perés, Muñoz Sebastián Andrés, Allievi Alberto, Orden Alberto, Trobo Rosana, Alvarez Analía, Eimon Alicia, Barreira Juan Carlos, Schneeberger Emilce, Sarano Judith, Hofman Julio, de Larrañaga Gabriela
Abstract excerpt
Systemic lupus erythematosus (SLE) is a systemic, autoimmune disorder. Monocyte chemoattractant protein 1 (MCP-1), a chemokine involved in the recruitment and migration of monocytes/macrophages, has been shown to be increased in the plasma of SLE patients. The aim of our study was to evaluate the possible association of the polymorphism -2518 of the MCP-1 gene with the risk of developing SLE, manifesting lupus...
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