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Article

Nonsense mutations in the lsa-like gene in Enterococcus faecalis isolates susceptible to lincosamides and Streptogramins A.

Antimicrobial agents and chemotherapy - 1 Jul 2003

Dina Julia, Malbruny Brigitte, Leclercq Roland

Abstract excerpt

The lsa gene confers intrinsic resistance to lincosamides and streptogramins A in Enterococcus faecalis, probably by active efflux. The lsa-like genes of two clinical isolates of E. faecalis susceptible to lincosamides and dalfopristin contained mutations that produced premature termination codons. Revertant mutants were obtained by selection on agar plates containing clindamycin.

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Source

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Identifiers

PMID: 12821484
DOI: 10.1128/AAC.47.7.2307-2309.2003
PMCID: PMC161836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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