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Cross-Resistance to Lincosamides, Streptogramins A, and Pleuromutilins Due to the <i>lsa</i> (C) Gene in <i>Streptococcus agalactiae</i> UCN70

19 Jan 2011

Abstract excerpt

Streptococcus agalactiae UCN70, isolated from a vaginal swab obtained in New Zealand, is resistant to lincosamides and streptogramins A (LS(A) phenotype) and also to tiamulin (a pleuromutilin). By whole-genome sequencing, we identified a 5,224-bp chromosomal extra-element that comprised a 1,479-bp open reading frame coding for an ABC protein (492 amino acids) 45% identical to Lsa(A), a protein related to...

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PMID: 21245447
DOI: 10.1128/aac.01068-10

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