Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A New Resistance Gene, linB , Conferring Resistance to Lincosamides by Nucleotidylation in Enterococcus faecium HM1025

1 Apr 1999

Abstract excerpt

Resistance to lincomycin and clindamycin in the clinical isolate Enterococcus faecium HM1025 is due to a ribosomal methylase encoded by an ermAM-like gene and the plasmid-mediated inactivation of these antibiotics. We have cloned and determined the nucleotide sequence of the gene responsible for the inactivation of lincosamides, linB. This gene encodes a 267-amino-acid lincosamide nucleotidyltransferase. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Antifungal resistance and susceptibility
Share to Antimicrobial Resistance in Staphylococcus

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10103201
DOI: 10.1128/aac.43.4.925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A New Resistance Gene, linB , Conferring Resistance to Lincosamides by Nucleotidylation in Enterococcus faecium HM1025PMID 10103201Read ↗

Lincomycin Resistance Gene lnu (D) in Streptococcus uberisSemantic proximity Read ↗

New MLS <sub>B</sub> Resistance Gene <i>erm</i> (43) in Staphylococcus lentusSemantic proximity Read ↗

A 32 kb nucleotide sequence from the region of the lincomycin-resistance gene (22 degrees-25 degrees) of the Bacillus subtilis chromosome and identification of the site of the lin-2 mutation.Semantic proximity Read ↗

The Novel Transcriptional Regulator LmbU Promotes Lincomycin Biosynthesis through Regulating Expression of Its Target Genes in Streptomyces lincolnensisSemantic proximity Read ↗

Emergence of 4',4"-aminoglycoside nucleotidyltransferase in enterococci.Semantic proximity Read ↗

Cloning and characterization of two genes from Streptomyces lividans that confer inducible resistance to lincomycin and macrolide antibiotics.Semantic proximity Read ↗

The Cfr rRNA Methyltransferase Confers Resistance to Phenicols, Lincosamides, Oxazolidinones, Pleuromutilins, and Streptogramin A AntibioticsSemantic proximity Read ↗

Molecular cloning and characterization of two lincomycin-resistance genes, lmrA and lmrB, from Streptomyces lincolnensis 78-11.Semantic proximity Read ↗

Lincosamide resistance mediated by lnu(C) (L phenotype) in a Streptococcus anginosus clinical isolate.Semantic proximity Read ↗

Lincomycin resistance mutations in two regions immediately downstream of the -10 region of lmr promoter cause overexpression of a putative multidrug efflux pump in Bacillus subtilis mutants.Semantic proximity Read ↗

Activity of the ketolide telithromycin is refractory to Erm monomethylation of bacterial rRNA.Semantic proximity Read ↗

Emergence of ArmA and RmtB aminoglycoside resistance 16S rRNA methylases in BelgiumSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.