Article
Multiple mutations in or adjacent to the conserved penicillin-binding protein motifs of the penicillin-binding protein 1A confer amoxicillin resistance to Helicobacter pylori.
Helicobacter - 1 Jun 2006
Gerrits Monique M, Godoy Anita P O, Kuipers Ernst J, Ribeiro Marcelo L, Stoof Jeroen, Mendonça Sergio, van Vliet Arnoud H M, Pedrazzoli José, Kusters Johannes G
Abstract excerpt
BACKGROUND: Amoxicillin-based therapies are highly effective for the treatment of Helicobacter pylori infections, but the efficacy may decrease as the incidence of amoxicillin resistance is increasing. So far, the molecular mechanism underlying stable amoxicillin resistance has only been identifi...
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