Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutations in penicillin-binding proteins 1, 2 and 3 are responsible for amoxicillin resistance in Helicobacter pylori.

The Journal of antimicrobial chemotherapy - 1 May 2008

Rimbara Emiko, Noguchi Norihisa, Kawai Takashi, Sasatsu Masanori

Abstract excerpt

OBJECTIVES: To elucidate the relationship between the mutations of penicillin-binding protein (PBP)1, PBP2 and PBP3 and amoxicillin resistance in Helicobacter pylori. METHODS: The mutations detected only in clinical amoxicillin-resistant strains were determined by comparison of the deduced amino acid sequences of PBP1(HP0597), PBP2(HP1556) and PBP3(HP1565) encoded by the pbp1, ftsI and pbp2 genes, respectively,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amoxicillin
Share to Anti-Bacterial Agents

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antimicrobial Resistance in Staphylococcus

Share to Drug Resistance, Bacterial

Share to Helicobacter pylori

Share to Helicobacter pylori-related gastroenterology studies

Share to Mutation

Share to Penicillin-Binding Proteins

Source

Identifiers

PMID: 18276599
DOI: 10.1093/jac/dkn051

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutations in penicillin-binding proteins 1, 2 and 3 are responsible for amoxicillin resistance in Helicobacter pylori.PMID 18276599Read ↗

Multiple mutations in or adjacent to the conserved penicillin-binding protein motifs of the penicillin-binding protein 1A confer amoxicillin resistance to Helicobacter pylori.Semantic proximity Read ↗

Multiple amino acid substitutions in penicillin-binding protein-1A confer amoxicillin resistance in refractory Helicobacter pylori infectionSemantic proximity Read ↗

Contribution of Specific Amino Acid Changes in Penicillin Binding Protein 1 to Amoxicillin Resistance in ClinicalHelicobacter pyloriisolatesSemantic proximity Read ↗

Alterations in penicillin-binding protein 1A confer resistance to beta-lactam antibiotics in Helicobacter pylori.Semantic proximity Read ↗

Synergistic effects of novel penicillin-binding protein 1A amino acid substitutions contribute to high-level amoxicillin resistance of Helicobacter pylori.Semantic proximity Read ↗

A change in PBP1 is involved in amoxicillin resistance of clinical isolates of Helicobacter pylori.Semantic proximity Read ↗

Resistance Mechanisms in an In Vitro-Selected Amoxicillin-Resistant Strain of Helicobacter pyloriSemantic proximity Read ↗

Genetic variations of penicillin-binding protein 1A: insights into the current status of amoxicillin-based regimens for Helicobacter pylori eradication in Malaysia.Semantic proximity Read ↗

Correlation between Substitutions in Penicillin‐Binding Protein 1 and Amoxicillin Resistance in <i>Helicobacter pylori</i>Semantic proximity Read ↗

Mutations in Genes Encoding Penicillin-Binding Proteins and Efflux Pumps Play a Role in β-Lactam Resistance in Helicobacter cinaedi.Semantic proximity Read ↗

Prevalence and Molecular Mechanisms of Amoxicillin Resistance Among Clinical Helicobacter pylori Isolates in Southwest China.Semantic proximity Read ↗

Identification of a Novel Penicillin-Binding Protein from Helicobacter pyloriSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.