Article
Mutations in penicillin-binding proteins 1, 2 and 3 are responsible for amoxicillin resistance in Helicobacter pylori.
The Journal of antimicrobial chemotherapy - 1 May 2008
Rimbara Emiko, Noguchi Norihisa, Kawai Takashi, Sasatsu Masanori
Abstract excerpt
OBJECTIVES: To elucidate the relationship between the mutations of penicillin-binding protein (PBP)1, PBP2 and PBP3 and amoxicillin resistance in Helicobacter pylori. METHODS: The mutations detected only in clinical amoxicillin-resistant strains were determined by comparison of the deduced amino...
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