Article
Initiation of RNA replication of cloned Taiwan-3 isolate of hepatitis delta virus genotype II in cultured cells.
Biochemical and biophysical research communications - 11 Jul 2003
Lin Feng-Ming, Lee Chuan-Mo, Wang Tzu-Chi, Chao Mei
Abstract excerpt
Hepatitis delta virus (HDV) genotype II is the predominant genotype in Taiwan and is associated with less progressive disease than genotype I. Although the Taiwan-3 (T3) clone was the first genotype II HDV isolated in Taiwan, its replication in cultured cells has not previously been established. Here, we demonstrate that cloned T3 HDV is capable of replicating in cultured cells. Furthermore, we show that: (1)....
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